The Team

Dr Sophie Cassidy


Research Associate


I am a clinical exercise physiologist (ACSM) interested in using lifestyle behaviours for the prevention and management of cardio-metabolic diseases.

A large part of my work involves leading clinical research studies. This includes exercise and metabolic testing, the design and implementation of interventions, and evaluation of results. During my PhD I ran a clinical trial which investigated the impact of High Intensity Intermittent Training (HIIT) on cardiac function and metabolism in adults with Type 2 diabetes.

I am now working on ‘Changing Health’ – an online behaviour change programme delivered via web and mobile phone app, which targets physical activity and diet to induce weight loss in those with pre-diabetes and Type 2 diabetes.

Alongside clinical research, I am also working on the UK Biobank cohort to investigate the role of lifestyle behaviours in cardio-metabolic disease from an epidemiological perspective, in collaboration with The University of Sydney.



Cassidy S, Thoma C, Hallsworth K., Parikh J, Hollingsworth KG, Taylor R, Jakovljevic DJ, Trenell MI (2016) High intensity intermittent exercise improves cardiac structure and function and reduces liver fat in patients with type 2 diabetes: A randomised controlled trial. Diabetologia. 2016 Jan; 59 (1):55-56. (DOI:10.1007/s00125-015-3741-2)

Houghton D, Jones TW, Cassidy S, Siervo M, MacGowan GA, Trenell MI, Jakovljevic DG. The effect of age on the relationship between cardiac and vascular function. Mech Ageing Dev. 2015 Nov 15;153:1-6. doi: 10.1016/j.mad.2015.11.001

Hallsworth K, Thoma C, Hollingsworth KG, Cassidy S, Anstee QM, Day CP, Trenell MI. Modified high-intensity interval training reduces liver fat and improves cardiac function in non-alcoholic fatty liver disease: a randomized controlled trial. Clin Sci (Lond). 2015 Dec;129(12):1097-105. doi: 10.1042/CS20150308.

Mann LW, Higgins DM, Peters CN, Cassidy S, Hodson KK, Coombs A, Taylor R, Hollingsworth KG. Accelerating MR Imaging Liver Steatosis Measurement Using Combined Compressed Sensing and Parallel Imaging: A Quantitative Evaluation. Radiology. 2016 Jan;278(1):247-56. doi: 10.1148/radiol.2015150320.

Jones TW, Houghton D, Cassidy S, MacGowan GA, Trenell MI, Jakovljevic DG. Bioreactance is a reliable method for estimating cardiac output at rest and during exercise. Br J Anaesth. 2015 Sep;115(3):386-91. doi: 10.1093/bja/aeu560. Epub 2015 Feb 6.


  • Nick Hayles Young Investigator Award at Diabetes UK Professional Conference – 2015
  • National ‘SET For Britain’ House of Commons poster presentation – 2015
  • Lilly Diabetes clinical science poster aware at Diabetes UK Professional Conference – 2014



Phone: 0191 208 8264

Email: sophie [DOT] cassidy [AT] newcastle [DOT] ac [DOT] uk